Description

Description of Codeine Phosphate 30mg

Codeine Phosphate 30mg is an opioid medication primarily used for the treatment of mild to moderate pain. It is also indicated for the relief of dry or painful cough and can be used to manage diarrhea in certain cases. Here’s a detailed breakdown of its characteristics, uses, dosage, and precautions.

Composition and Formulation

• Active Ingredient: Each tablet contains 30 mg of codeine phosphate.
• Form: Oral tablets are typically taken with water. They may be prescribed alone or in combination with other analgesics like paracetamol or ibuprofen.

Mechanism of Action

Codeine works by binding to specific receptors in the brain (μ-opioid receptors), which helps to block pain signals and alter the perception of pain. Additionally, it suppresses the activity in the brain that triggers coughing.

Indications

1. Pain Relief: Codeine phosphate is indicated for patients older than 12 years who require relief from acute moderate pain that is not adequately managed by non-opioid analgesics.
2. Cough Suppression: It can also be used to alleviate dry cough.
3. Diarrhea Management: In some cases, it may be prescribed to treat diarrhea.

Dosage Guidelines

• Adults: The recommended dose for adults is typically 30 mg taken every 6 hours as needed, not exceeding a total daily dose of 240 mg.
• Children (12 years and older): The dosage should be based on body weight, usually ranging from 0.5 to 1 mg/kg every 6 hours as necessary.
• Duration of Treatment: Treatment duration should generally be limited to three days; if effective pain relief is not achieved, further consultation with a physician is advised.

Precautions and Contraindications

• Age Restrictions: Not recommended for children under 12 years old due to risks associated with respiratory depression.
• Respiratory Issues: Should be avoided in patients with severe asthma or other significant respiratory conditions.
• Liver/Kidney Impairment: Caution should be exercised in patients with liver or kidney dysfunction, as these conditions can affect drug metabolism and excretion.
• Drug Interactions: Codeine can interact with various medications (e.g., antidepressants, alcohol) that may enhance sedative effects or increase the risk of respiratory depression.

Side Effects

Common side effects include:

• Drowsiness
• Dizziness
• Nausea and vomiting
• Constipation

Serious side effects may involve:

• Respiratory depression (slow or shallow breathing)
• Allergic reactions (swelling, rash)
• Dependence and withdrawal symptoms upon abrupt cessation after prolonged use.